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Characterization of SMAD3 Gene Variants for Possible Roles in Ventricular Septal Defects and Other Congenital Heart Diseases
BACKGROUND: Nodal/TGF signaling pathway has an important effect at early stages of differentiation of human embryonic stem cells in directing them to develop into different embryonic lineages. SMAD3 is a key intracellular messenger regulating factor in the Nodal/TGF signaling pathway, playing import...
Autores principales: | Li, Fei-Feng, Zhou, Jing, Zhao, Dan-Dan, Yan, Peng, Li, Xia, Han, Ying, Li, Xian-Shu, Wang, Gui-Yu, Yu, Kai-Jiang, Liu, Shu-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482402/ https://www.ncbi.nlm.nih.gov/pubmed/26110764 http://dx.doi.org/10.1371/journal.pone.0131542 |
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