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Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis

African trypanosomiasis is a deadly neglected disease caused by the extracellular parasite Trypanosoma brucei. Current therapies are characterized by high drug toxicity and increasing drug resistance mainly associated with loss-of-function mutations in the transporters involved in drug import. The i...

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Detalles Bibliográficos
Autores principales: Unciti-Broceta, Juan D., Arias, José L., Maceira, José, Soriano, Miguel, Ortiz-González, Matilde, Hernández-Quero, José, Muñóz-Torres, Manuel, de Koning, Harry P., Magez, Stefan, Garcia-Salcedo, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482409/
https://www.ncbi.nlm.nih.gov/pubmed/26110623
http://dx.doi.org/10.1371/journal.ppat.1004942