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Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis
African trypanosomiasis is a deadly neglected disease caused by the extracellular parasite Trypanosoma brucei. Current therapies are characterized by high drug toxicity and increasing drug resistance mainly associated with loss-of-function mutations in the transporters involved in drug import. The i...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482409/ https://www.ncbi.nlm.nih.gov/pubmed/26110623 http://dx.doi.org/10.1371/journal.ppat.1004942 |