Rates of Chemical Cleavage of DNA and RNA Oligomers Containing Guanine Oxidation Products

[Image: see text] The nucleobase guanine in DNA (dG) and RNA (rG) has the lowest standard reduction potential of the bases, rendering it a major site of oxidative damage in these polymers. Mapping the sites at which oxidation occurs in an oligomer via chemical reagents utilizes hot piperidine for cl...

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Detalles Bibliográficos
Autores principales: Fleming, Aaron M., Alshykhly, Omar, Zhu, Judy, Muller, James G., Burrows, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482417/
https://www.ncbi.nlm.nih.gov/pubmed/25853314
http://dx.doi.org/10.1021/acs.chemrestox.5b00096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482417/
https://www.ncbi.nlm.nih.gov/pubmed/25853314
http://dx.doi.org/10.1021/acs.chemrestox.5b00096

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