Cargando…
Rates of Chemical Cleavage of DNA and RNA Oligomers Containing Guanine Oxidation Products
[Image: see text] The nucleobase guanine in DNA (dG) and RNA (rG) has the lowest standard reduction potential of the bases, rendering it a major site of oxidative damage in these polymers. Mapping the sites at which oxidation occurs in an oligomer via chemical reagents utilizes hot piperidine for cl...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2015
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482417/ https://www.ncbi.nlm.nih.gov/pubmed/25853314 http://dx.doi.org/10.1021/acs.chemrestox.5b00096 |