Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction

[Image: see text] A platform technology has been developed and tested for delivery of intracellular-acting peptides through electrostatically complexed nanoparticles, or nano-polyplexes, formulated from an anionic endosomolytic polymer and cationic therapeutic peptides. This delivery platform has be...

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Detalles Bibliográficos
Autores principales: Evans, Brian C., Hocking, Kyle M., Kilchrist, Kameron V., Wise, Eric S., Brophy, Colleen M., Duvall, Craig L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482421/
https://www.ncbi.nlm.nih.gov/pubmed/26004140
http://dx.doi.org/10.1021/acsnano.5b00491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482421/
https://www.ncbi.nlm.nih.gov/pubmed/26004140
http://dx.doi.org/10.1021/acsnano.5b00491

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