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Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction
[Image: see text] A platform technology has been developed and tested for delivery of intracellular-acting peptides through electrostatically complexed nanoparticles, or nano-polyplexes, formulated from an anionic endosomolytic polymer and cationic therapeutic peptides. This delivery platform has be...
Autores principales: | Evans, Brian C., Hocking, Kyle M., Kilchrist, Kameron V., Wise, Eric S., Brophy, Colleen M., Duvall, Craig L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482421/ https://www.ncbi.nlm.nih.gov/pubmed/26004140 http://dx.doi.org/10.1021/acsnano.5b00491 |
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