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Selection and Characterization of DNA Aptamers Targeting All Four Serotypes of Dengue Viruses

Dengue viruses (DENVs) are members of Flaviviridae family, which are associated with human disease. The envelope (E) protein plays an important role in viral infection. However, there is no effective antibody for clinical treatment due to antibody dependent enhancement of infection. In this study, u...

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Detalles Bibliográficos
Autores principales: Chen, Heng-Li, Hsiao, Wen-Hsin, Lee, Hsiang-Chi, Wu, Suh-Chin, Cheng, Jya-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482433/
https://www.ncbi.nlm.nih.gov/pubmed/26110785
http://dx.doi.org/10.1371/journal.pone.0131240