EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells

KRAS mutational status is considered a negative predictive marker of the response to anti-EGFR therapies in colorectal cancer (CRC) patients. However, conflicting data exist regarding the variable response to EGFR-targeted therapy. The effects of oncogenic KRAS on downstream targets were studied in...

Descripción completa

Detalles Bibliográficos
Autores principales: Roda, Desamparados, Castillo, Josefa, Telechea-Fernández, Marcelino, Gil, Anabel, López-Rodas, Gerardo, Franco, Luís, González-Rodríguez, Patricia, Roselló, Susana, Pérez-Fidalgo, J. Alejandro, García-Trevijano, Elena R., Cervantes, Andrés, Zaragozá, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482484/
https://www.ncbi.nlm.nih.gov/pubmed/26110767
http://dx.doi.org/10.1371/journal.pone.0130543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482484/
https://www.ncbi.nlm.nih.gov/pubmed/26110767
http://dx.doi.org/10.1371/journal.pone.0130543

Ejemplares similares