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EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells
KRAS mutational status is considered a negative predictive marker of the response to anti-EGFR therapies in colorectal cancer (CRC) patients. However, conflicting data exist regarding the variable response to EGFR-targeted therapy. The effects of oncogenic KRAS on downstream targets were studied in...
Autores principales: | Roda, Desamparados, Castillo, Josefa, Telechea-Fernández, Marcelino, Gil, Anabel, López-Rodas, Gerardo, Franco, Luís, González-Rodríguez, Patricia, Roselló, Susana, Pérez-Fidalgo, J. Alejandro, García-Trevijano, Elena R., Cervantes, Andrés, Zaragozá, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482484/ https://www.ncbi.nlm.nih.gov/pubmed/26110767 http://dx.doi.org/10.1371/journal.pone.0130543 |
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