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Gamma-Smooth Muscle Actin Expression Is Associated with Epithelial-Mesenchymal Transition and Stem-Like Properties in Hepatocellular Carcinoma

BACKGROUND AND AIMS: The prognosis of hepatocellular carcinoma (HCC) is hampered by frequent tumour recurrence and metastases. Epithelial-Mesenchymal Transition (EMT) is now recognized as a key process in tumour invasion, metastasis and the generation of cancer initiating cells. The morphological id...

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Detalles Bibliográficos
Autores principales: Benzoubir, Nassima, Mussini, Charlotte, Lejamtel, Charlène, Dos Santos, Alexandre, Guillaume, Claire, Desterke, Christophe, Samuel, Didier, Bréchot, Christian, Bourgeade, Marie-Françoise, Guettier, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482489/
https://www.ncbi.nlm.nih.gov/pubmed/26110787
http://dx.doi.org/10.1371/journal.pone.0130559