Cargando…

Regulation of Pro-Apoptotic Phosphorylation of Kv2.1 K(+) Channels

Caspase activity during apoptosis is inhibited by physiological concentrations of intracellular K(+). To enable apoptosis in injured cortical and hippocampal neurons, cellular loss of this cation is facilitated by the insertion of Kv2.1 K(+) channels into the plasma membrane via a Zn(2+)/CaMKII/SNAR...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Kai, McCord, Meghan C., Hartnett, Karen A., Aizenman, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482604/
https://www.ncbi.nlm.nih.gov/pubmed/26115091
http://dx.doi.org/10.1371/journal.pone.0129498