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Regulation of Pro-Apoptotic Phosphorylation of Kv2.1 K(+) Channels
Caspase activity during apoptosis is inhibited by physiological concentrations of intracellular K(+). To enable apoptosis in injured cortical and hippocampal neurons, cellular loss of this cation is facilitated by the insertion of Kv2.1 K(+) channels into the plasma membrane via a Zn(2+)/CaMKII/SNAR...
Autores principales: | He, Kai, McCord, Meghan C., Hartnett, Karen A., Aizenman, Elias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482604/ https://www.ncbi.nlm.nih.gov/pubmed/26115091 http://dx.doi.org/10.1371/journal.pone.0129498 |
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