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A Rodent Model of Chikungunya Virus Infection in RAG1 (-/-) Mice, with Features of Persistence, for Vaccine Safety Evaluation
Chikungunya virus (CHIKV) is a positive sense, single stranded RNA virus in the genus Alphavirus, and the etiologic agent of epidemics of severe arthralgia in Africa, Asia, Europe and, most recently, the Americas. CHIKV causes chikungunya fever (CHIK), a syndrome characterized by rash, fever, and de...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482609/ https://www.ncbi.nlm.nih.gov/pubmed/26115459 http://dx.doi.org/10.1371/journal.pntd.0003800 |