A Rodent Model of Chikungunya Virus Infection in RAG1 (-/-) Mice, with Features of Persistence, for Vaccine Safety Evaluation

Chikungunya virus (CHIKV) is a positive sense, single stranded RNA virus in the genus Alphavirus, and the etiologic agent of epidemics of severe arthralgia in Africa, Asia, Europe and, most recently, the Americas. CHIKV causes chikungunya fever (CHIK), a syndrome characterized by rash, fever, and de...

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Detalles Bibliográficos
Autores principales: Seymour, Robert L., Adams, A. Paige, Leal, Grace, Alcorn, Maria D. H., Weaver, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482609/
https://www.ncbi.nlm.nih.gov/pubmed/26115459
http://dx.doi.org/10.1371/journal.pntd.0003800

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