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Saccharomyces cerevisiae Eukaryotic Elongation Factor 1A (eEF1A) Is Methylated at Lys-390 by a METTL21-Like Methyltransferase

The human methyltransferases (MTases) METTL21A and VCP-KMT (METTL21D) were recently shown to methylate single lysine residues in Hsp70 proteins and in VCP, respectively. The yet uncharacterized MTase encoded by the YNL024C gene in Saccharomyces cerevisiae shows high sequence similarity to METTL21A a...

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Detalles Bibliográficos
Autores principales: Jakobsson, Magnus E., Davydova, Erna, Małecki, Jędrzej, Moen, Anders, Falnes, Pål Ø.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482628/
https://www.ncbi.nlm.nih.gov/pubmed/26115316
http://dx.doi.org/10.1371/journal.pone.0131426