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Malthusian Parameters as Estimators of the Fitness of Microbes: A Cautionary Tale about the Low Side of High Throughput

The maximum exponential growth rate, the Malthusian parameter (MP), is commonly used as a measure of fitness in experimental studies of adaptive evolution and of the effects of antibiotic resistance and other genes on the fitness of planktonic microbes. Thanks to automated, multi-well optical densit...

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Detalles Bibliográficos
Autores principales: Concepción-Acevedo, Jeniffer, Weiss, Howard N., Chaudhry, Waqas Nasir, Levin, Bruce R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482697/
https://www.ncbi.nlm.nih.gov/pubmed/26114477
http://dx.doi.org/10.1371/journal.pone.0126915