Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes

High rates of error-prone replication result in the rapid accumulation of genetic diversity of RNA viruses. Recent studies suggest that mutation rates are selected for optimal viral fitness and that modest variations in replicase fidelity may be associated with viral attenuation. Arthropod-borne vir...

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Detalles Bibliográficos
Autores principales: Van Slyke, Greta A., Arnold, Jamie J., Lugo, Alex J., Griesemer, Sara B., Moustafa, Ibrahim M., Kramer, Laura D., Cameron, Craig E., Ciota, Alexander T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482725/
https://www.ncbi.nlm.nih.gov/pubmed/26114757
http://dx.doi.org/10.1371/journal.ppat.1005009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482725/
https://www.ncbi.nlm.nih.gov/pubmed/26114757
http://dx.doi.org/10.1371/journal.ppat.1005009

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