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Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes
High rates of error-prone replication result in the rapid accumulation of genetic diversity of RNA viruses. Recent studies suggest that mutation rates are selected for optimal viral fitness and that modest variations in replicase fidelity may be associated with viral attenuation. Arthropod-borne vir...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482725/ https://www.ncbi.nlm.nih.gov/pubmed/26114757 http://dx.doi.org/10.1371/journal.ppat.1005009 |