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Targeting of a Fixed Bacterial Immunogen to Fc Receptors Reverses the Anti-Inflammatory Properties of the Gram-Negative Bacterium, Francisella tularensis, during the Early Stages of Infection

Production of pro-inflammatory cytokines by innate immune cells at the early stages of bacterial infection is important for host protection against the pathogen. Many intracellular bacteria, including Francisella tularensis, the agent of tularemia, utilize the anti-inflammatory cytokine IL-10, to ev...

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Detalles Bibliográficos
Autores principales: Babadjanova, Zulfia, Wiedinger, Kari, Gosselin, Edmund J., Bitsaktsis, Constantine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482730/
https://www.ncbi.nlm.nih.gov/pubmed/26114641
http://dx.doi.org/10.1371/journal.pone.0129981