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Surgery for Glioblastoma: Impact of the Combined Use of 5-Aminolevulinic Acid and Intraoperative MRI on Extent of Resection and Survival

BACKGROUND: There is rising evidence that in glioblastoma(GBM) surgery an increase of extent of resection(EoR) leads to an increase of patient’s survival. Based on histopathological assessments tumor depiction of Gd-DTPA enhancement and 5-aminolevulinic-acid-fluorescence(5-ALA) might be synergistic...

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Detalles Bibliográficos
Autores principales: Coburger, Jan, Hagel, Vincent, Wirtz, Christian Rainer, König, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482740/
https://www.ncbi.nlm.nih.gov/pubmed/26115409
http://dx.doi.org/10.1371/journal.pone.0131872