Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform

Tumor stroma and growth factors provide a survival environment to tumor cells and can modulate their chemoresistance by dysregulating several signal pathways. In this study, we fabricated a three-dimensional (3D) microfluidic chip using polydimethylsiloxane (PDMS) to investigate the impact of hepato...

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Detalles Bibliográficos
Autores principales: Ying, Li, Zhu, Ziwei, Xu, Zhiyun, He, Tianrui, Li, Encheng, Guo, Zhe, Liu, Fen, Jiang, Chunmeng, Wang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482748/
https://www.ncbi.nlm.nih.gov/pubmed/26115510
http://dx.doi.org/10.1371/journal.pone.0129593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482748/
https://www.ncbi.nlm.nih.gov/pubmed/26115510
http://dx.doi.org/10.1371/journal.pone.0129593

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