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Anti-obesity and metabolic efficacy of the β3-adrenergic agonist, CL316243, in mice at thermoneutrality compared to 22°C

OBJECTIVE: Mice are typically housed at environmental temperatures below thermoneutrality, whereas humans live near thermoneutrality. This difference affects energy physiology and, potentially, anti-obesity drug efficacy. Here we compare β3-adrenergic agonist treatment at thermoneutrality (30°C) ver...

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Detalles Bibliográficos
Autores principales: Xiao, Cuiying, Goldgof, Margalit, Gavrilova, Oksana, Reitman, Marc L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482793/
https://www.ncbi.nlm.nih.gov/pubmed/26053335
http://dx.doi.org/10.1002/oby.21124