The Human Epilepsy Mutation GABRG2(Q390X) Causes Chronic Subunit Accumulation and Neurodegeneration

Genetic epilepsy and neurodegenerative diseases are two common neurological disorders conventionally viewed as being unrelated. A subset of patients with severe genetic epilepsies with impaired development and often death respond poorly to anticonvulsant drug therapy, suggesting a need for new thera...

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Detalles Bibliográficos
Autores principales: Kang, Jing-Qiong, Shen, Wangzhen, Zhou, Chengwen, Xu, Dong, Macdonald, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482801/
https://www.ncbi.nlm.nih.gov/pubmed/26005849
http://dx.doi.org/10.1038/nn.4024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482801/
https://www.ncbi.nlm.nih.gov/pubmed/26005849
http://dx.doi.org/10.1038/nn.4024

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