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High expression of endoplasmic reticulum chaperone grp94 is a novel molecular hallmark of malignant plasma cells in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a hematologic malignancy that is characterized by the proliferation of abnormal bone marrow plasma cells (BMPC) and overproduction of immunoglobulin or light chains with evidence of end-organ damage such as bone damage, anemia, hypercalcemia, and renal dysfunctio...

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Detalles Bibliográficos
Autores principales: Chhabra, Saurabh, Jain, Sandeep, Wallace, Caroline, Hong, Feng, Liu, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483199/
https://www.ncbi.nlm.nih.gov/pubmed/26108343
http://dx.doi.org/10.1186/s13045-015-0177-6