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Active Degradation Explains the Distribution of Nuclear Proteins during Cellular Senescence

The amount of cellular proteins is a crucial parameter that is known to vary between cells as a function of the replicative passages, and can be important during physiological aging. The process of protein degradation is known to be performed by a series of enzymatic reactions, ranging from an initi...

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Detalles Bibliográficos
Autores principales: Giampieri, Enrico, De Cecco, Marco, Remondini, Daniel, Sedivy, John, Castellani, Gastone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483236/
https://www.ncbi.nlm.nih.gov/pubmed/26115222
http://dx.doi.org/10.1371/journal.pone.0118442