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Detailed assessment of gene activation levels by multiple hypoxia-responsive elements under various hypoxic conditions
OBJECTIVE: HIF-1/HRE pathway is a promising target for the imaging and the treatment of intractable malignancy (HIF-1; hypoxia-inducible factor 1, HRE; hypoxia-responsive element). The purposes of our study are: (1) to assess the gene activation levels resulting from various numbers of HREs under va...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483249/ https://www.ncbi.nlm.nih.gov/pubmed/25249501 http://dx.doi.org/10.1007/s12149-014-0901-2 |