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Quantifying the Antiviral Effect of IFN on HIV-1 Replication in Cell Culture

Type-I interferons (IFNs) induce the expression of hundreds of cellular genes, some of which have direct antiviral activities. Although IFNs restrict different steps of HIV replication cycle, their dominant antiviral effect remains unclear. We first quantified the inhibition of HIV replication by IF...

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Detalles Bibliográficos
Autores principales: Ikeda, Hiroki, Godinho-Santos, Ana, Rato, Sylvie, Vanwalscappel, Bénédicte, Clavel, François, Aihara, Kazuyuki, Iwami, Shingo, Mammano, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483772/
https://www.ncbi.nlm.nih.gov/pubmed/26119462
http://dx.doi.org/10.1038/srep11761