Lack of a significant change in caffeine metabolism in underweight children as determined by the caffeine breath test

OBJECTIVE: Limited data from pharmacokinetic studies in underweight and severely malnourished children have indicated an impaired activity of their hepatic enzymes. We used the caffeine breath test to assess the metabolising activity of cytochrome P450 1A2 (CYP1A2) enzyme in underweight children. ME...

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Detalles Bibliográficos
Autores principales: Oshikoya, K A, Sammons, H, Smith, K, Choonara, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Drug Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483790/
https://www.ncbi.nlm.nih.gov/pubmed/25897037
http://dx.doi.org/10.1136/archdischild-2014-308017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483790/
https://www.ncbi.nlm.nih.gov/pubmed/25897037
http://dx.doi.org/10.1136/archdischild-2014-308017

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