Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells

Although inactivating frameshift mutations in the Transforming growth factor beta receptor type 2 (TGFBR2) gene are considered as drivers of microsatellite unstable (MSI) colorectal tumorigenesis, consequential alterations of the downstream target proteome are not resolved completely. Applying a cli...

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Detalles Bibliográficos
Autores principales: Lee, Jennifer, Fricke, Fabia, Warnken, Uwe, Schnölzer, Martina, Kopitz, Jürgen, Gebert, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484253/
https://www.ncbi.nlm.nih.gov/pubmed/26114631
http://dx.doi.org/10.1371/journal.pone.0131506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484253/
https://www.ncbi.nlm.nih.gov/pubmed/26114631
http://dx.doi.org/10.1371/journal.pone.0131506

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