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Core promoter sequence in yeast is a major determinant of expression level

The core promoter is the regulatory sequence to which RNA polymerase is recruited and where it acts to initiate transcription. Here, we present the first comprehensive study of yeast core promoters, providing massively parallel measurements of core promoter activity and of TSS locations and relative...

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Detalles Bibliográficos
Autores principales: Lubliner, Shai, Regev, Ifat, Lotan-Pompan, Maya, Edelheit, Sarit, Weinberger, Adina, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484384/
https://www.ncbi.nlm.nih.gov/pubmed/25969468
http://dx.doi.org/10.1101/gr.188193.114