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Unraveling determinants of transcription factor binding outside the core binding site

Binding of transcription factors (TFs) to regulatory sequences is a pivotal step in the control of gene expression. Despite many advances in the characterization of sequence motifs recognized by TFs, our ability to quantitatively predict TF binding to different regulatory sequences is still limited....

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Detalles Bibliográficos
Autores principales: Levo, Michal, Zalckvar, Einat, Sharon, Eilon, Dantas Machado, Ana Carolina, Kalma, Yael, Lotam-Pompan, Maya, Weinberger, Adina, Yakhini, Zohar, Rohs, Remo, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484385/
https://www.ncbi.nlm.nih.gov/pubmed/25762553
http://dx.doi.org/10.1101/gr.185033.114