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The landscape of genomic imprinting across diverse adult human tissues

Genomic imprinting is an important regulatory mechanism that silences one of the parental copies of a gene. To systematically characterize this phenomenon, we analyze tissue specificity of imprinting from allelic expression data in 1582 primary tissue samples from 178 individuals from the Genotype-T...

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Detalles Bibliográficos
Autores principales: Baran, Yael, Subramaniam, Meena, Biton, Anne, Tukiainen, Taru, Tsang, Emily K., Rivas, Manuel A., Pirinen, Matti, Gutierrez-Arcelus, Maria, Smith, Kevin S., Kukurba, Kim R., Zhang, Rui, Eng, Celeste, Torgerson, Dara G., Urbanek, Cydney, Li, Jin Billy, Rodriguez-Santana, Jose R., Burchard, Esteban G., Seibold, Max A., MacArthur, Daniel G., Montgomery, Stephen B., Zaitlen, Noah A., Lappalainen, Tuuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484390/
https://www.ncbi.nlm.nih.gov/pubmed/25953952
http://dx.doi.org/10.1101/gr.192278.115