Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells

Cancer cells recruit normal cells such as fibroblasts to establish reactive microenvironments. Via metabolic stress, catabolism and inflammation, these cancer-associated fibroblasts set up a synergistic relationship with tumour cells, that contributes to their malignancy and resistance to therapy. G...

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Detalles Bibliográficos
Autores principales: Peiris-Pagès, Maria, Sotgia, Federica, Lisanti, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484415/
https://www.ncbi.nlm.nih.gov/pubmed/25915429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484415/
https://www.ncbi.nlm.nih.gov/pubmed/25915429

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