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The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration

HOTTIP is a long non-coding RNA (lncRNA) transcribed from the 5′ tip of the HOXA locus and is associated with the polycomb repressor complex 2 (PRC2) and WD repeat containing protein 5 (WDR5)/mixed lineage leukemia 1 (MLL1) chromatin modifying complexes. HOTTIP is expressed in pancreatic cancer cell...

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Detalles Bibliográficos
Autores principales: Cheng, Yating, Jutooru, Indira, Chadalapaka, Gayathri, Corton, J. Christopher, Safe, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484423/
https://www.ncbi.nlm.nih.gov/pubmed/25912306