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The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration
HOTTIP is a long non-coding RNA (lncRNA) transcribed from the 5′ tip of the HOXA locus and is associated with the polycomb repressor complex 2 (PRC2) and WD repeat containing protein 5 (WDR5)/mixed lineage leukemia 1 (MLL1) chromatin modifying complexes. HOTTIP is expressed in pancreatic cancer cell...
Autores principales: | Cheng, Yating, Jutooru, Indira, Chadalapaka, Gayathri, Corton, J. Christopher, Safe, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484423/ https://www.ncbi.nlm.nih.gov/pubmed/25912306 |
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