RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer

We have demonstrated that RNA-dependent protein kinase (PKR) and its downstream protein p-eIF2α are independent prognostic markers for overall survival in lung cancer. In the current study, we further investigate the interaction between PKR and AMPK in lung tumor tissue and cancer cell lines. We exa...

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Detalles Bibliográficos
Autores principales: Guo, Chengcheng, Hao, Chuncheng, Shao, RuPing, Fang, Bingliang, Correa, Arlene M., Hofstetter, Wayne L., Roth, Jack A., Behrens, Carmen, Kalhor, Neda, Wistuba, Ignacio I., Swisher, Stephen G., Pataer, Apar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484443/
https://www.ncbi.nlm.nih.gov/pubmed/25798539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484443/
https://www.ncbi.nlm.nih.gov/pubmed/25798539

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