Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment

Lipogenesis inhibition was reported to induce apoptosis and repress proliferation of cancer cells while barely affecting normal cells. Lipins exhibit dual function as enzymes catalyzing the dephosphorylation of phosphatidic acid to diacylglycerol and as co-transcriptional regulators. Thus, they are...

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Detalles Bibliográficos
Autores principales: Brohée, Laura, Demine, Stéphane, Willems, Jérome, Arnould, Thierry, Colige, Alain C., Deroanne, Christophe F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484455/
https://www.ncbi.nlm.nih.gov/pubmed/25834103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484455/
https://www.ncbi.nlm.nih.gov/pubmed/25834103

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