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Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU

BCL6B is a potential tumor suppressor in human gastric cancer, but the regulation and mechanism of BCL6B in human hepatocellular carcinogenesis remain unclear. This study is to explore the epigenetic change and mechanism of BCL6B in human hepatocellular carcinoma (HCC). Nineteen hepatic cancer cell...

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Detalles Bibliográficos
Autores principales: Li, Xin, Yu, Jie, Brock, Malcolm V., Tao, Qian, Herman, James G., Liang, Ping, Guo, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484475/
https://www.ncbi.nlm.nih.gov/pubmed/25909168