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LncRNA-ATB promotes trastuzumab resistance and invasion-metastasis cascade in breast cancer

Trastuzumab resistance is leading cause of mortality in HER2-positive breast cancers, and the role of TGF-β-induced epithelial-mesenchymal transition (EMT) in trastuzumab resistance is well established, but the involvement of lncRNAs in trastuzumab resistance is still unknown. Here, we generated tra...

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Detalles Bibliográficos
Autores principales: Shi, Sheng-Jia, Wang, Li-Juan, Yu, Bo, Li, Yun-Hui, Jin, Yong, Bai, Xiao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484483/
https://www.ncbi.nlm.nih.gov/pubmed/25871474