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Nuclear lymphocyte-specific protein tyrosine kinase and its interaction with CR6-interacting factor 1 promote the survival of human leukemic T cells

Overexpression and hyperactivation of lymphocyte-specific protein tyrosine kinase (Lck) have been associated with leukemia development. We previously showed that, other than its known function as a cytoplasmic signal transducer, Lck also acts as a nuclear transcription factor in mouse leukemic cells...

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Detalles Bibliográficos
Autores principales: VAHEDI, SHAHROOZ, CHUEH, FU-YU, DUTTA, SUJOY, CHANDRAN, BALA, YU, CHAO-LAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484609/
https://www.ncbi.nlm.nih.gov/pubmed/25997448
http://dx.doi.org/10.3892/or.2015.3990