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Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data

Apart from genetic mutations, epigenetic alteration is a common phenomenon that contributes to neoplastic transformation in colorectal cancer. Transcriptional silencing of tumor-suppressor genes without changes in the DNA sequence is explained by the existence of promoter hypermethylation. To test t...

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Detalles Bibliográficos
Autores principales: KOK-SIN, TEOW, MOKHTAR, NORFILZA MOHD, HASSAN, NUR ZARINA ALI, SAGAP, ISMAIL, ROSE, ISA MOHAMED, HARUN, ROSLAN, JAMAL, RAHMAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484611/
https://www.ncbi.nlm.nih.gov/pubmed/25997610
http://dx.doi.org/10.3892/or.2015.3993