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Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells

Pristimerin (PM) is a promising anticancer agent that has exhibited strong antiproliferative and apoptosis-inducing activity in various types of cancer cells. In the present study, we investigated the role of telomerase in mediating the antitumor activity of PM in pancreatic ductal adenocarcinoma (P...

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Detalles Bibliográficos
Autores principales: DEEB, DORRAH, GAO, XIAOHUA, LIU, YONGBO, PINDOLIA, KIRIT, GAUTAM, SUBHASH C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484616/
https://www.ncbi.nlm.nih.gov/pubmed/25997419
http://dx.doi.org/10.3892/or.2015.3989