Quantitative analysis of mRNA expression levels and DNA methylation profiles of three neighboring genes: FUS1, NPRL2/G21 and RASSF1A in non-small cell lung cancer patients

BACKGROUND: Tumor suppressor gene (TSG) inactivation plays a crucial role in carcinogenesis. FUS1, NPRL2/G21 and RASSF1A are TSGs from LUCA region at 3p21.3, a critical chromosomal region in lung cancer development. The aim of the study was to analyze and compare the expression levels of these 3 TSG...

Descripción completa

Detalles Bibliográficos
Autores principales: Pastuszak-Lewandoska, Dorota, Kordiak, Jacek, Migdalska-Sęk, Monika, Czarnecka, Karolina H., Antczak, Adam, Górski, Paweł, Nawrot, Ewa, Kiszałkiewicz, Justyna M., Domańska, Daria, Brzeziańska-Lasota, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484633/
https://www.ncbi.nlm.nih.gov/pubmed/26112163
http://dx.doi.org/10.1186/s12931-015-0230-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484633/
https://www.ncbi.nlm.nih.gov/pubmed/26112163
http://dx.doi.org/10.1186/s12931-015-0230-6

Ejemplares similares