Sphingosine kinase 1 as an anticancer therapeutic target

The development of chemotherapeutic resistance is a major challenge in oncology. Elevated sphingosine kinase 1 (SK1) levels is predictive of a poor prognosis, and SK1 overexpression may confer resistance to chemotherapeutics. The SK/sphingosine-1-phosphate (S1P)/sphingosine-1-phosphate receptor (S1P...

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Detalles Bibliográficos
Autores principales: Gao, Ying, Gao, Fei, Chen, Kan, Tian, Mei-li, Zhao, Dong-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484649/
https://www.ncbi.nlm.nih.gov/pubmed/26150697
http://dx.doi.org/10.2147/DDDT.S83288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484649/
https://www.ncbi.nlm.nih.gov/pubmed/26150697
http://dx.doi.org/10.2147/DDDT.S83288

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