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Sphingosine kinase 1 as an anticancer therapeutic target

The development of chemotherapeutic resistance is a major challenge in oncology. Elevated sphingosine kinase 1 (SK1) levels is predictive of a poor prognosis, and SK1 overexpression may confer resistance to chemotherapeutics. The SK/sphingosine-1-phosphate (S1P)/sphingosine-1-phosphate receptor (S1P...

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Detalles Bibliográficos
Autores principales:	Gao, Ying, Gao, Fei, Chen, Kan, Tian, Mei-li, Zhao, Dong-li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484649/ https://www.ncbi.nlm.nih.gov/pubmed/26150697 http://dx.doi.org/10.2147/DDDT.S83288

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