Improving dissolution and oral bioavailability of pranlukast hemihydrate by particle surface modification with surfactants and homogenization

The present study was carried out to develop an oral formulation of pranlukast hemihydrate with improved dissolution and oral bioavailability using a surface-modified microparticle. Based on solubility measurements, surface-modified pranlukast hemihydrate microparticles were manufactured using the s...

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Detalles Bibliográficos
Autores principales: Ha, Eun-Sol, Baek, In-hwan, Yoo, Jin-Wook, Jung, Yunjin, Kim, Min-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484661/
https://www.ncbi.nlm.nih.gov/pubmed/26150699
http://dx.doi.org/10.2147/DDDT.S87738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484661/
https://www.ncbi.nlm.nih.gov/pubmed/26150699
http://dx.doi.org/10.2147/DDDT.S87738

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