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P53 codon 72 polymorphism, human papillomavirus infection, and their interaction to oral carcinoma susceptibility

BACKGROUND: Tumor suppressor gene p53 plays an important role in the maintenance of the genomic integrity, and mutation in the gene may alter an individual’s susceptibility to various carcinomas. P53 Arg72Pro or codon 72 polymorphism has been indicated to increase the risk of developing certain canc...

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Detalles Bibliográficos
Autores principales: Hou, Jun, Gu, Ying, Hou, Wei, Wu, Song, Lou, Yin, Yang, Wenyu, Zhu, Ling, Hu, Yukun, Sun, Ming, Xue, Haowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484699/
https://www.ncbi.nlm.nih.gov/pubmed/26123760
http://dx.doi.org/10.1186/s12863-015-0235-7