DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs

Pancreatic β-cells are the body's sole source of circulating insulin and essential for the maintenance of blood glucose homeostasis. Levels of up to 66 “disallowed” genes, which are strongly expressed and play housekeeping roles in most other mammalian tissues, are unusually low in β-cells. The...

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Detalles Bibliográficos
Autores principales: Martinez-Sanchez, Aida, Nguyen-Tu, Marie-Sophie, Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484783/
https://www.ncbi.nlm.nih.gov/pubmed/26038943
http://dx.doi.org/10.1210/me.2015-1059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484783/
https://www.ncbi.nlm.nih.gov/pubmed/26038943
http://dx.doi.org/10.1210/me.2015-1059

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