High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

RAS and BRAF mutations impact treatment and prognosis of metastatic colorectal cancer patients (mCRC), but the knowledge is based on trial patients usually not representative for the general cancer population. Patient characteristics, treatment and efficacy according to KRAS, BRAF and MSI status wer...

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Detalles Bibliográficos
Autores principales: Sorbye, Halfdan, Dragomir, Anca, Sundström, Magnus, Pfeiffer, Per, Thunberg, Ulf, Bergfors, Monica, Aasebø, Kristine, Eide, Geir Egil, Ponten, Fredrik, Qvortrup, Camilla, Glimelius, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484806/
https://www.ncbi.nlm.nih.gov/pubmed/26121270
http://dx.doi.org/10.1371/journal.pone.0131046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484806/
https://www.ncbi.nlm.nih.gov/pubmed/26121270
http://dx.doi.org/10.1371/journal.pone.0131046

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